Google pirate v3 extended1/1/2023 (d.) Boxplots reporting the changes of ARGs conferring resistance to beta-lactam antibiotics in patients treated with this class of antibiotic and in controls.įig. (c.) Boxplots reporting the changes of selected components of the resistome and summarizing data shown in panels a. Like antibiotics’ abbreviations, bars are coloured according to antibiotic classes (see Abbreviations section). The y-axis thus reports the number of reads mapping to a given class per million of bacterial reads. Reads mapping to genes conferring resistance to the same class of antibiotic were summed and normalized to the number of reads mapping to bacteria. Antibiotics’ abbreviations are reported above bars and coloured according to the corresponding antibiotic class. When a time point is not included, faeces were not sampled. For each patient, we selected genes encoding resistance against the antibiotics used in treatments till a given time point. (a.-b.) Bar plots representing the abundance of antibiotic-resistance-encoding genes in faecal samples at time points (D7, D14, D30 and D90) of patients assigned to 7 days (a.) or 14 days of antibiotic therapy (b.). 1 Resistome abundance compared to antibiotic therapy. The Lancet Regional Health – Western Pacificįig.The Lancet Regional Health – Southeast Asia. The Lancet Gastroenterology & Hepatology.
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